Cyclosporine-Induced Posterior Reversible Leukoencephalopathy Syndrome With Reduced Cerebral Perfusion.
- Author:
Tae Ho KANG
1
;
Kee Yong CHO
;
Sang Min SUNG
;
Dae Soo JUNG
;
Kyu Hyun PARK
;
Han Jin CHO
Author Information
1. Department of Neurology, Pusan National University Hospital, Pusan National University Graduate School of Medicine, Busan, Korea. chohj75@gmail.com
- Publication Type:Case Report
- Keywords:
Posterior reversible leukoencephalopathy syndrome;
Cyclosporine;
Perfusion computed tomography
- MeSH:
Brain;
Cyclosporine;
Edema;
Humans;
Ischemia;
Leukoencephalopathies*;
Perfusion*;
Vasoconstriction
- From:Journal of the Korean Neurological Association
2013;31(4):270-272
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Posterior reversible leukoencephalopathy syndrome (PRLS) is a disorder that is characterized by reversible white-matter edema affecting the posterior regions of the brain. There are rare cases in which cyclosporine has been cited as a medication responsible for PRLS, which causes hypoperfused ischemia by endothelial injury and vasoconstriction, with resultant vasogenic edema. A PRLS patient in whom the condition was induced by cyclosporine is described herein. Perfusion computed tomography revealed a clinically relevant hypoperfused area, including the zones of vasogenic edema.
