Hypoglycemia due to Focal Nesidioblastosis in a Patient with Type 2 Diabetes Mellitus.
10.4093/kdj.2009.33.3.251
- Author:
Eun Jung LEE
1
;
Kee Ho SONG
;
Suk Kyeong KIM
;
Seong Hwan CHANG
;
Dong Lim KIM
Author Information
1. Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. dlkim@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Diabetes mellitus;
Nesidioblastosis;
Hypoglycemia
- MeSH:
Calcium;
Diabetes Mellitus;
Diabetes Mellitus, Type 2;
Diazoxide;
Head;
Humans;
Hypoglycemia;
Middle Aged;
Nesidioblastosis;
Pancreas;
Prednisolone
- From:Korean Diabetes Journal
2009;33(3):251-256
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a 45-year-old man with type 2 diabetes who presented with recurrent hypoglycemia. Biochemical and imagingstudies did not show any mass-like lesion in the pancreas, so prednisolone and diazoxide were administered for the treatment of hypoglycemia. However, the hypoglycemia persisted during and after the medical treatment. A selective arterial calcium stimulation test was performed and revealed a suspicious lesion at the head of the pancreas. The patient underwent enucleation of the pancreas head lesion. The lesion was confirmed histologically to be focal nesidioblastosis and surgical resection was successfully performed. The patient showed no hypoglycemic symptoms postoperatively.
