A Case of Classic Kaposi's Sarcoma Showing Good Response to Radiotherapy.
- Author:
Jee Ook KIM
1
;
Jae Hong PARK
;
Jun Hyoung PARK
;
Young Wook RYOO
;
Byung Chun KIM
;
Kyu Suk LEE
Author Information
1. Department of Dermatology, Keimyung University School of Medicine, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
Kaposi's sarcoma;
Radiotherapy
- MeSH:
Aged;
Biopsy;
Dermis;
Endothelial Cells;
Humans;
Hyperpigmentation;
Lower Extremity;
Radiotherapy*;
Sarcoma, Kaposi*;
Skin;
von Willebrand Factor
- From:Korean Journal of Dermatology
2000;38(12):1646-1650
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kaposi's sarcoma is a neoplasm of multifocal origin which manifests primarily as vascular nodules in the skin and other organs. We report a case of classic Kaposi's sarcoma in a 79-year-old man who had asymptomatic dark-brown macules, papules and nodules on his Rt. lower extremities. The biopsy specimen showed typical histopathologic features of Kaposi's sarcoma including dilated, bizarre-shaped vessels, endothelial cell proliferation, and spindle cell formation with vascular slits throughout the dermis. Many of the spindle-shaped cells associated with the proliferating vessels in Kaposi's sarcoma lesion expressed factor VIII-related antigen. Initially he was treated with 4,000 rads of radiation(200 rad per day for 20 successive days), and after two months 2,500 rads of radiation(500 rad per day for 5 successive days). Three months after radiotherapy, skin lesions were healed leaving hyperpigmentation.
