A Case of Necrobiosis Lipoidica with Prominent Cholesterol Cleft.
- Author:
Hyo Chan JANG
1
;
Byung Cheol JUNG
;
Sang Won KIM
Author Information
1. Department of Dermatology, School of Medicine, Catholic University of Daegu, Daegu, Korea.
- Publication Type:Case Report
- Keywords:
Necrobiosis lipoidica;
Cholesterol clefts
- MeSH:
Adult;
Biopsy;
Blood Glucose;
Cholesterol*;
Dermis;
Fibrosis;
Granuloma;
Humans;
Necrobiosis Lipoidica*;
Necrobiotic Disorders*;
Necrobiotic Xanthogranuloma;
Paraproteinemias;
Subcutaneous Tissue;
Triglycerides
- From:Korean Journal of Dermatology
2000;38(12):1656-1659
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report an unusual case of necrobiosis lipoidica with prominent cholesterol clefts in a 36-year-old man who had developed multiple, 0.5~5cm in diameter, round to oval-shaped erythematous plaques on both shins for over 3 years. Laboratory findings showed the following; cholesterol, 250mg/dl; triglyceride, 208mg/dl; blood sugar level fasting/2-h postprandial, 101/92mg/dl; and other findings were within normal limits or negative. There was no paraproteinemia. The biopsy specimen showed various lymphohistiocytic granuloma with many giants cell in the mid and deep dermis, and septal fibrosis in the subcutaneous tissue. There were also extensive areas of necrobiosis with prominent cholesterol clefts mimicking necrobiotic xanthogranuloma.
