Factors Related to the Diagnostic Yield of Flexible Bronchoscopy without Guidance in Bronchoscopically Invisible Peripheral Lung Lesions.
10.4046/trd.2017.80.3.284
- Author:
Hye Seon KANG
1
;
Jick Hwan HA
;
Hyeon Hui KANG
;
Chang Dong YEO
;
Chin Kook RHEE
;
Sung Kyoung KIM
;
Hwa Sik MOON
;
Sang Haak LEE
Author Information
1. Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. agmante@gmail.com
- Publication Type:Original Article
- Keywords:
Bronchoscopy;
Lung;
Bronchi;
Multidetector Computed Tomography
- MeSH:
Bronchi;
Bronchoscopy*;
Humans;
Korea;
Logistic Models;
Lung*;
Multidetector Computed Tomography;
Pleura;
Retrospective Studies
- From:Tuberculosis and Respiratory Diseases
2017;80(3):284-290
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: We aimed to analyze the factors predicting the diagnostic performance of flexible bronchoscopy without guidance in peripheral lung lesions that are endoscopically invisible. METHODS: This was a retrospective study conducted in St. Paul's Hospital, The Catholic University of Korea, between January 2007 and March 2013. We included all patients who received bronchoscopy during this period. The analyzed variables were age, sex, the etiology of the lesion, lesion size, distance from the pleura, and presence of the bronchus sign. We used multiple logistic regression analysis to identify the significant independent factors associated with diagnostic yield. RESULTS: We included 151 patients in this study. The overall diagnostic yield was 58.3%. The sensitivity was 43.2% for malignant disease and 78.1% for benign disease. The benign lung lesions (p<0.001), lesion size (p=0.015), presence of the exposed type of bronchus sign (p<0.001), and presence of cavitary lung lesions (p=0.005) were factors influencing the yield of flexible bronchoscopy by univariate analysis. In a multivariate logistic regression analysis, the exposed type of bronchus sign and benign lung lesions were independent predicting factors (odds ratio [OR]: 27.95; 95% confidence interval [CI], 7.56–103.32; p<0.001 and OR, 4.91; 95% CI, 1.76–13.72; p=0.002). CONCLUSION: The presence of the exposed type of bronchus sign and benign lung lesions are determining factors of the diagnostic yield in flexible bronchoscopy in evaluating peripheral lesions that are not endoscopically visible.
