A Case of Posterior Reversible Encephalopathy Syndrome during Cyclosporine Therapy in a Child with Steroid Resistant Nephrotic Syndrome.
- Author:
Min Hee JEONG
1
;
Joo Hoon LEE
;
Mi Sun YUM
;
Tae Sung KO
;
Young Seo PARK
Author Information
1. Department of pediatrics, Asan Medical Center, College of Medicine University of Ulsan Seoul, Korea. yspark@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Steroid resistant nephrotic syndrome;
Posterior reversible encephalopathy syndrome;
Cyclosporine
- MeSH:
Blood Pressure;
Child*;
Cyclosporine*;
Drug Therapy;
Eclampsia;
Female;
Follow-Up Studies;
Headache;
Humans;
Hypertension;
Lethargy;
Nephrotic Syndrome*;
Posterior Leukoencephalopathy Syndrome*;
Pregnancy;
Seizures
- From:Journal of the Korean Society of Pediatric Nephrology
2007;11(1):92-99
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The posterior reversible encephalopathy syndrome(PRES) is characterized clinically by a combination of acute or subacute confusion, lethargy, visual disturbance, and seizures. PRES has been described in various clinical settings, including severe hypertension, chemotherapy, eclampsia, and seizure. We report a case of a 7-year-old girl who had taken cyclosporine for steroid resistant nephrotic syndrome. Twenty one days after the cyclosporine therapy, she was admitted due to generalized tonic clonic seizure and headache. Her blood pressure was 170/90 mmHg. Magnetic resonance(MR) imaging showed necrotic/cystic lesions involving the bilateral parieto-occipital region. After discontinuation of cyclosporine, and control of blood pressure, she had no more seizure and headache. The follow-up MR examination which was performed 6 months later showed the decreased extent of the lesion.
