A Case of Primary Cutaneous Diffuse Large B-cell Lymphoma,Leg Type Which Metastasized to the Brain.
- Author:
Yun Mi KIM
1
;
Sung Keun KIM
;
Sang Hoon LEE
;
Young Lip PARK
;
Jongsuk LEE
;
Kyu Uang WHANG
;
Susie CHIN
Author Information
1. Department of Dermatology, Soonchunhyang University College of Medicine, Seoul, Korea. snolomas@hosp.sch.ac.kr
- Publication Type:Case Report
- Keywords:
Leg type;
Metastasis;
Primary cutaneous diffuse large B-cell lymphoma;
WHO-EORTC classification
- MeSH:
B-Lymphocytes;
Brain;
Humans;
Leg;
Lymphoma;
Lymphoma, B-Cell;
Lymphoma, B-Cell, Marginal Zone;
Male;
Middle Aged;
Neoplasm Metastasis;
Prognosis;
Skin;
World Health Organization
- From:Korean Journal of Dermatology
2009;47(10):1149-1153
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In the WHO-EORTC (World Health Organization-European Organization for Research and Treatment of Cancer) classification, the primary cutaneous B-cell lymphomas were divided into 4 groups: primary cutaneous marginal zone B-cell lymphoma, primary cutaneous follicle center cell lymphoma, primary cutaneous diffuse large B-cell lymphoma, other, and primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL LT). PCLBCL LT is known to have more aggressive clinical behavior and a worse prognosis than the other groups of primary cutaneous B-cell lymphomas. We report here on a case of PCLBCL LT in a 55-year-old male who presented witha multiple erythematous nodules on the right leg. After chemotherapy, the skin lesions had almost cleared, but afterward the tumor was revealed to have metastasized to the brain during 1 year.
