Isotretinoin Treatment for the Recalcitrant Acne on a Patient with Apert Syndrome.
- Author:
Jiwon BYUN
1
;
Sunghyub HAN
;
Bo Hee YANG
;
Hee Jin SONG
;
Hyeon Sook LEE
;
Seung Gyu LEE
;
Jeonghyun SHIN
;
Gwang Seong CHOI
Author Information
1. Department of Dermatology, College of Medicine, Inha University, Incheon, Korea. garden@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Acne;
Apert syndrome;
Isotretinoin
- MeSH:
Acne Vulgaris;
Acrocephalosyndactylia;
Cleft Palate;
Cranial Sutures;
Exophthalmos;
Forearm;
Humans;
Hypertelorism;
Isotretinoin;
Puberty;
Receptor, Fibroblast Growth Factor, Type 2;
Syndactyly;
Thorax
- From:Korean Journal of Dermatology
2009;47(10):1196-1198
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Apert syndrome is a rare genetic craniofacial disorder associated with premature fusion of multiple cranial sutures and syndactyly. It is caused by mutation in the fibroblast growth factor receptor 2 genes. The clinical findings are characterized by the typical dysmorphic facial features, including hypertelorism, proptosis and cleft palate. Most of these patients have widespread, severe acne involving the face, chest, back and forearms during puberty and the acne is unresponsive to conventional treatments. We report here on a patient with the recalcitrant acne of Apert syndrome and the patient had failed to respond to conventional acne treatment, but the acne was successfully treated with isotretinoin
