A Case of Reticulate Pigmented Anomaly of the Flexures (Dowling-Degos Disease).
- Author:
Gyo Shin KANG
1
;
Woo Tae KO
;
Moo Kyu SUH
;
Tae Jung JANG
Author Information
1. Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea. smg@dongguk.ac.kr
- Publication Type:Case Report
- Keywords:
Dowling-Degos disease
- MeSH:
Axilla;
Groin;
Humans;
Hyperpigmentation;
Male;
Middle Aged;
Neck;
Skin Diseases, Genetic;
Skin Diseases, Papulosquamous
- From:Korean Journal of Dermatology
2009;47(10):1199-1202
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Reticulate pigmented anomaly of the flexures is a rare autosomal dominant genodermatosis, and this is also known as Dowling-Degos disease. The clinical symptoms are characterized by the progressive evolution of small hyperpigmented macules in a reticulate distribution, and this shows a predilection for the flexural regions, including the axillae, antecubital fossae, inframammary regions, neck and groin. The histopathology of reticulate pigmented anomaly of the flexures typically shows filiform epithelial down-growth of the epidermal rete ridges along with basal hyperpigmentation. We report here on a case of reticulate pigmented anomaly of the flexures in a 45-year-old male who showed multiple, asymptomatic, scaly brownish reticulated macules on the flexural areas.