Lipoprotein(a) and Lipoprotein(a) Phenotype in Restenosis after Percutaneous Transluminal Coronary Angioplasty.
10.4070/kcj.1995.25.2.439
- Author:
Dong Wan SEO
;
Jae Joong KIM
;
Wonki MIN
;
Jae Kwan SONG
;
Seong Wook PARK
;
Seung Jung PARK
;
Jong Koo LEE
- Publication Type:Original Article
- Keywords:
Percutaneous transluminal coronary angioplasty;
Lipid parameters;
Lipoprotein(a);
Lipoprotein(a) phenotype
- MeSH:
Angioplasty, Balloon, Coronary*;
Apoproteins;
Coronary Angiography;
Exercise Test;
Follow-Up Studies;
Humans;
Hypertension;
Lipoprotein(a)*;
Phenotype*;
Prospective Studies;
Thallium
- From:Korean Circulation Journal
1995;25(2):439-450
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The purpose of the study was to investigate prospectively the relation of lipoprotein(a)[Lp(a)],apoproteins and serum lipid parameters to restenosis after percutaneous transluminal coronary angioplasyt(PTCA). METHODS: One hundred and forty-five patients who received successful PTCA were enrolled and their serum levels of lipids, apoproteins and Lp(a) were measured before PTCA. After 6 months of follow-up, the patients were reevaluated for the development of restenosis by coronary angiography, treadmill test or thallium scan. RESULTS: A total 137 patients could be followed. Restenosis occurred in 71 patients(52%). Clinical parameters(e.g. age, sex, hypertension, diabetes, smoking) and angiographic parameters(e.g. lesion site, type and degree of stenosis) were not significantly different between the group without restenosis and the group with restenosis. Lipid parameters and apoproteins were not associated with restenosis. Lp(a) and Lp(a) phenotype analysis showed no significant difference between the two gruops. CONCLUSION: Serum lipid parameters, apoproteins and Lp(a) concentration are not associated with restenosis after PTCA and cannot be used as predictios of restenosis.
