A case of Hemolytic Disease of the Newborn due to Anti-Mi a Antibody.
- Author:
Sang Eun LEE
1
;
Jung KIM
;
Mi Sook YOON
;
Eun Young SONG
;
Kyou Sup HAN
Author Information
1. Department of Pediatrics, Masan Samsung Hospital, College of Medicine, Sungkyungwan University, Masan, Korea.
- Publication Type:Case Report
- Keywords:
Miltenberger;
hemolytic disease of the newborn;
anti-Mia antibody;
first case;
Korea
- MeSH:
Bilirubin;
Coombs Test;
Epitopes;
Humans;
Hyperbilirubinemia;
Infant;
Infant, Newborn*;
Korea;
Male;
Mothers;
Phenotype
- From:Korean Journal of Blood Transfusion
2004;15(2):231-235
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of hemolytic disease of the newborn caused by anti-Mia (Miltenberger) antibody. Full term male infant was admitted due to hyperbilirubinemia on second day of life. Total serum bilirubin level was 8.6 mg/dL at 12 hours of age and 12.3 mg/dL at 24 hours of age. The blood group of patient and his mother were both RhD positive B type. Direct antiglobulin test was strongly positive in the patient, and testing of maternal serum and patient's serum against a red cell panel including cells known to carry the antigenic determinants of some Miltenberger phenotypes revealed the presence of anti-Mia . Testing of paternal red cells and patient's red cell against anti-Mia serum revealed positive reaction. This report documents the first case of hemolytic disease of the newborn due to anti-Mi a in Korea.
