Impact of dialysis modality on technique survival in end-stage renal disease patients.
10.3904/kjim.2016.31.1.106
- Author:
Jong Hak LEE
1
;
Sun Hee PARK
;
Jeong Hoon LIM
;
Young Jae PARK
;
Sang Un KIM
;
Kyung Hee LEE
;
Kyung Hoon KIM
;
Seung Chan PARK
;
Hee Yeon JUNG
;
Owen KWON
;
Ji Young CHOI
;
Jang Hee CHO
;
Chan Duck KIM
;
Yong Lim KIM
Author Information
1. Clinical Research Center for End Stage Renal Disease in Korea, Daegu, Korea. ylkim@knu.ac.kr
- Publication Type:Comparative Study ; Multicenter Study ; Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Survival;
Hemodialysis;
Peritoneal dialysis;
Body mass index;
Diabetes
- MeSH:
Adult;
Aged;
Body Mass Index;
Humans;
Kidney Failure, Chronic/diagnosis/mortality/*therapy;
Male;
Middle Aged;
Nutritional Status;
Peritoneal Dialysis/adverse effects/mortality;
Prospective Studies;
*Renal Dialysis/adverse effects/mortality;
Republic of Korea;
Risk Factors;
Time Factors;
Treatment Outcome
- From:The Korean Journal of Internal Medicine
2016;31(1):106-115
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: This study analyzed the risk factors for technique survival in dialysis patients and compared technique survival rates between hemodialysis (HD) and peritoneal dialysis (PD) in a prospective cohort of Korean patients. METHODS: A total of 1,042 patients undergoing dialysis from September 2008 to June 2011 were analyzed. The dialysis modality was defined as that used 90 days after commencing dialysis. Technique survival was compared between the two dialysis modalities, and the predictive risk factors were evaluated. RESULTS: The dialysis modality was an independent risk factor predictive of technique survival. PD had a higher risk for technique failure than HD (hazard ratio [HR], 10.8; 95% confidence interval [CI], 1.9 to 62.0; p = 0.008) during a median follow-up of 11.0 months. In the PD group, a high body mass index (BMI) was an independent risk factor for technique failure (HR, 1.3; 95% CI, 1.0 to 1.8; p = 0.036). Peritonitis was the most common cause of PD technique failure. The difference in technique survival between PD and HD was more prominent in diabetic patients with a good nutritional status and in non-diabetic patients with a poor nutritional status. CONCLUSIONS: In a prospective cohort of Korean patients with end-stage renal disease, PD was associated with a higher risk of technique failure than HD. Diabetic patients with a good nutritional status and non-diabetic patients with a poor nutritional status, as well as patients with a higher BMI, had an inferior technique survival rate with PD compared to HD.
