Comparison of the Clinicopathologic Features and the Survival Rates in Young and Elderly Patients with Gastric Cancer.
10.5230/jkgca.2006.6.4.257
- Author:
Chan Young KIM
1
;
Doo Hyun YANG
Author Information
1. Department of Surgery, Chonbuk National University Medical School, Jeonju, Korea. ydh@chonbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Gastric cancer;
Young patient;
Elderly patient;
Clinicopathologic feature;
Outcome of treatment
- MeSH:
Aged*;
Chemotherapy, Adjuvant;
Female;
Gastrectomy;
Humans;
Lymph Nodes;
Mortality;
Stomach Neoplasms*;
Survival Rate*
- From:Journal of the Korean Gastric Cancer Association
2006;6(4):257-262
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We analyzed the clinicopathologic features, including treatment and outcome, and the survival rates between young and elderly patients with gastric cancer. MATERIALS AND METHODS: Clinical information was reviewed for 1086 patients who had undergone a gastrectomy for gastric cancer during a 10-year period from 1990 to 1999, and the patients were assigned to one of two groups: the A group (<40 years of age, 91 patients) and the B group (> or =70 years of age, 85 patients). RESULTS: Compared to the B group, the A group had more females (47.3% vs 32.9%), a greater frequency of family history of cancer (15.4% vs 3.5%), and greater proportions of histologically poorly differentiated tumors (84.5% vs 40.2%) and Lauren diffuse-type tumors (69.1% vs 35.1%)(P<0.05). There was no difference in TNM stage. Cardiopulmonary co-morbidities were more in the B group, respectively, 1.1% (A group) and 11.8% (B group)(P<0.01), but the morbidity and the mortality were similar. Although there was no difference in curability, the B group underwent less aggressive operations in lymph-node dissection above D3 and had a shorter operation time, a smaller number of retrieved lymph nodes, and less adjuvant chemotherapy (P<0.001). However, there were no differences in the disease-specific 5-year survival rates, 67.6% and 67.0% respectively. CONCLUSION: Young and elderly patients with gastric cancer had different clinicopathological features. Especially, elderly patients underwent relatively less aggressive treatment. In spite of these facts, the outcome of treatment and the disease-specific survival rates were not different.
