A case of human toxocariasis with hypereosinophilic syndrome confirmed by serologic test.
- Author:
Jeong Hee CHOI
1
;
Jeong Yeob SONG
;
Hong Suk IM
;
Yoo Jin SUH
;
Young Mok LEE
;
Sun HUH
;
Dong Ho NAHM
;
Hae Sim PARK
Author Information
1. Department of Allergy and Clinical Immunology, Ajou University, School of Medicine, Suwon, Korea. hspark@madang.ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Toxocariasis;
eosinophilia;
TES antigens;
IgE antibodies;
immunoblot
- MeSH:
Animals;
Diagnosis;
Dogs;
Enzyme-Linked Immunosorbent Assay;
Eosinophilia;
Humans*;
Hypereosinophilic Syndrome*;
Immunoglobulin E;
Immunoglobulin G;
Liver;
Parasites;
Sensitivity and Specificity;
Serologic Tests*;
Stomach;
Toxocara;
Toxocara canis;
Toxocariasis*
- From:Journal of Asthma, Allergy and Clinical Immunology
2001;21(6):1211-1216
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Human toxocariasis is defined as the infection of a human host by the larval stages of Toxocara canis, a common intestinal parasite of dogs. We experienced a patient with hypereosinophilic syndrome involving liver and stomach caused by human toxocariasis. The diagnosis of toxocariasis was confirmed by detecting serum specific IgE antibody to Toxocara excretory-secretory antigens (TES-Ag) by ELISA and IgG immunoblot analysis, with high sensitivity and specificity for the diagnosis of toxocariasis. Toxocariasis should be considered one of the causative diseases inducing hypereosinophilic syndrome in this country.
