Signet Ring Cell Carcinoma of the Extrahepatic Bile Duct.
- Author:
Eun Young LEE
1
;
Chan KIM
;
Min Joo KIM
;
Jung Yeop PARK
;
Seung Woo PARK
;
Si Young SONG
;
Jae Bock CHUNG
;
Hogeun KIM
;
Seungmin BANG
Author Information
1. Division of Gastroenterology, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea. bang7028@yuhs.ac
- Publication Type:Case Report
- Keywords:
Signet ring cell carcinoma;
Extrahepatic bile duct
- MeSH:
Bile Ducts, Extrahepatic;
Carcinoma, Signet Ring Cell;
Chemoradiotherapy;
Common Bile Duct;
Humans;
Jaundice;
Middle Aged;
Pancreaticoduodenectomy;
Positron-Emission Tomography and Computed Tomography;
Pruritus;
Pylorus;
Recurrence
- From:Gut and Liver
2010;4(3):402-406
- CountryRepublic of Korea
- Language:English
-
Abstract:
Most tumors affecting the extrahepatic bile duct are adenocarcinomas; the other histologic types occur only rarely. We herein report the extremely rare case of signet ring cell carcinoma (SRCC) originating from the extrahepatic bile duct. A 55-year-old man was hospitalized for jaundice and pruritus. Computed tomography and positron emission tomography suggested the presence of distal extrahepatic bile-duct cancer. He underwent a pylorus preserving pancreaticoduodenectomy. A histologic study confirmed a signet ring cell neoplasm of the distal common bile duct. Because the upper resection margin was invaded by the tumor, he received postoperative concurrent chemoradiotherapy and four cycles of chemotherapy. The patient has survived with no evidence of recurrence for 2 years. This is the second case of primary SRCC of the distal extrahepatic bile duct reported in the literature; further reports of cases are warranted to determine the nature of SRCC in the extrahepatic bile duct.
