Two Cases of Sclerotic Fibroma.
- Author:
Chang Ho YOON
1
;
Young Suck RO
Author Information
1. Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea. romio@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Sclerotic fibroma
- MeSH:
Collagen;
Eosinophils;
Fibroma*;
Hamartoma Syndrome, Multiple;
Humans;
Hyalin;
Sclerosis;
Skin;
Tongue
- From:Korean Journal of Dermatology
2004;42(11):1466-1469
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sclerotic fibroma is an uncommom fibrotic neoplasm that can occur as solitary lesions in otherwise healthy individuals. Multiple sclerotic fibromas of the skin are considered a cutaneous marker of multiple hamartoma syndrome or Cowden's disease. Sclerotic fibroma was first described by Weary et al. in the tongue of a patient with Cowden's disease in 1972. Rapini and Golitz described the sporadic occurrence of histologically identical tumors, and they suggested the names `hypocellular fibroma' and `sclerotic fibromas of the skin' for these lesions in 1990. The characteristics of sclerotic fibromas include hypocellularity and stromal sclerosis with eosinophilic, hyalinized collagen bundles in a parallel or whorled arrangement. We report two cases of solitary sclerotic fibroma of the skin not associated with Cowden's disease.
