A Case of Cutaneous Polyarteritis Nodosa Associated With Chronic Hepatitis B Infection.
- Author:
Kapsok LI
1
;
Dong Hun LEE
;
Kyung Chan PARK
;
Sang Woong YOUN
Author Information
1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Cutaneous polyarteritis nodosa;
Hepatitis B virus;
Lamivudine
- MeSH:
Hepatitis B virus;
Hepatitis B, Chronic*;
Hepatitis, Chronic*;
Lamivudine;
Polyarteritis Nodosa*;
Treatment Outcome;
Vasculitis
- From:Korean Journal of Dermatology
2004;42(11):1470-1474
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Polyarteritis nodosa (PAN) is regarded as an immune-complex mediated vasculitis and can present as extrahepatic manifestation of hepatitis B virus (HBV) infection. When treating HBV-associated PAN with immunosuppressive agent such as systemic steroid, the possibility of viral reactivation should be kept in mind and eagerly checked. Herein we report a case of HBV-associated cutaneous polyarteritis nodosa and its treatment outcome with combination therapy of steroid and antiviral agent, lamivudine for 6 weeks. Our experience suggests that more clinical data should be collected to determine the proper indication and end-point of antiviral therapy in chronic HBV carriers who receive immunosuppressant therapy.
