A Case of Angiocentic T-Cell Lymphoma Achieving Initial Complete Remission with CVP Chemotherapy.
- Author:
Jong Kyu YANG
1
;
Sung Wook KIM
;
Seung Churl PAIK
;
Chung Won KIM
;
Suk Young PARK
Author Information
1. Department of Dermatology, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Angiocentric T cell ymphoma;
CVP chemotherapy
- MeSH:
Drug Therapy*;
Herpesvirus 4, Human;
In Situ Hybridization;
Lymphocytes;
Lymphoma, T-Cell*;
Lymphoma, T-Cell, Peripheral;
Prognosis;
T-Lymphocytes*;
Vincristine
- From:Korean Journal of Dermatology
1997;35(4):772-777
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Angiocentric T-cell lymphoma is a subtype of peripheral T-cell lymphoma and histologically characterized by angiocentric and angioinvasive infiltration of lymphoid cells with varying degrees of cytological atypia, leading to angiodestruction. This disease represents the malignant end in the histological spectrum of angiocentric immunproliferative lesions. This malignancy is commonly a disease with considerable morbidity and is often fatal. However, primary cutaneous angiocentric T-cell lymphoma has a tendency to give a favorable prognosis. Epstein-Barr virus can be identified in involved tissue by immunostaining or by in situ hybridization and it is considered significant in the prognosis. We report a case of cutaneous angiocentric T-cell lymphoma, where the Epstein-Barr virus was identified within neoplastic cells. CVP(cyclophosphamide, vincristine, prednisone) chemotherapy was instigated and an initial complete remission was achieved.
