Necrotizing Fasciitis in a Patient with Systemic Lupus Erythematosus.
- Author:
Hye In CHO
1
;
Hak CHANG
Author Information
1. Department of Plastic and Reconstructive Surgery, Seoul National University, College of Medicine, Seoul, Korea. hchang@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Necrotizing fasciitis;
Systemic lupus erythematosus
- MeSH:
Adult;
Anti-Bacterial Agents;
Autoimmune Diseases;
Canes;
Debridement;
Diagnosis, Differential;
Early Diagnosis;
Emergencies;
Fasciitis, Necrotizing;
Female;
Follow-Up Studies;
Humans;
Leg;
Lupus Erythematosus, Systemic;
Outpatients;
Porphyrins;
Rare Diseases;
Skin;
Skin Transplantation;
Soft Tissue Infections;
Transplants
- From:Journal of the Korean Society of Plastic and Reconstructive Surgeons
2011;38(3):309-314
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Necrotizing fasciitis is a life-threatening, destructive soft tissue infection with a very high rate of mortality that needs early diagnosis and aggressive treatment. Systemic Lupus Erythematosus(SLE) is a systemic, autoimmune disease and it's major cause of mortality is an infection. But necrotizing fasciitis in SLE is very rare and there have been only 22 cases reported in the literatures. We reported a patient of necrotizing fasciitis with SLE and reviewed 22 others from literature research. METHODS: A 40-year-old female patient with a history of SLE for 6 years came to the emergency room. The patient complained of severe pain and swelling on her right leg. She was diagnosed as necrotizing fasciitis and underwent emergency fasciotomy. As wound cultures showed variable organisms, she was treated with broad-spectrum antibiotics and underwent several surgical debridements. Then, the wound was treated with the V.A.C(Vacuum Assisted Closure) device and split thickness skin grafting was performed two times. RESULTS: Skin graft was well taken within 2 weeks after operations and the patient was discharged to outpatient follow up. There was no complication related with surgery and she could walk without cane after 3 months. CONCLUSION: We treated a necrotizing fasciitis in a patient with SLE and reviewed 22 others from literature research. The case presented here suggests that necrotizing fasciitis is a rare disease in SLE patients, but should be considered in the differential diagnosis of soft tissue infection in SLE patients. A high index of suspicion is needed for early diagnosis and proper management in these patients.
