The Impact of Concomitant Splenectomy on the Portal Pressure in Patients with Liver Cirrhosis.
- Author:
Kyung Hee NAM
1
;
Yoon Jin HWANG
;
Jae Min CHEON
;
Sang Geol KIM
;
Young Guk YEUN
Author Information
1. Department of Surgery, Kyungpook National University, College of Medicine, Daegu, Korea. yjhwang@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Concomitant splenectomy;
Portal venous pressure;
Portal triad clamping
- MeSH:
Constriction;
Esophageal and Gastric Varices;
Factor IX;
Humans;
Laparotomy;
Liver;
Liver Cirrhosis;
Portal Pressure;
Splenectomy;
Thrombocytopenia;
Veins
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2008;12(3):156-161
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Concomitant splenectomy in cirrhotic patients is known to ameliorate the tendency to bleed and it decreases the portal venous pressure (PVP). However, the direct measurement of the change in the PVP after concomitant splenectomy has not yet been reported. We tried to measure the change of the PVP before and after splenectomy. METHODS: From March 2000 to May 2006, 18 patients underwent anatomical liver resection with concomitant splenectomy. All the patients had liver cirrhosis, thrombocytopenia and/or esophageal varix. Through the 5 French feeding tube, which was inserted into the right gastroepiploic vein after laparotomy, we directly measured the PVP before and after splenectomy, and also under portal triad clamping (PTC). RESULTS: After splenectomy, the PVP decreased significantly from 261.11+/-45.87 mmH2O to 221.11+/-38.48 mmH2O (p<0.05). Under PTC, the PVP decreased significantly from 605.00+/-116.48 mmH2O to 513.89+/-70.56 mmH2O (p<0.05). CONCLUSION: Concomitant splenectomy in patients with liver cirrhosis resulted in a significant reduction of the PVP.
