Successful Pediatric ABO-Incompatible Kidney Transplantation without Pretransplant Plasmapheresis: Report of a Case.
10.4285/jkstn.2014.28.1.39
- Author:
A Lan LEE
1
;
Hyun Ok KIM
;
Kyu Ha HUH
;
Myoung Soo KIM
Author Information
1. Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. ysms91@yuhs.ac
- Publication Type:Case Report
- Keywords:
Pediatric kidney transplantation;
ABO-incompatible kidney transplantation;
Plasmapheresis
- MeSH:
Adult;
Child;
Humans;
Infant;
Kidney Failure, Chronic;
Kidney Transplantation*;
Kidney*;
Living Donors;
Male;
Necrosis;
Plasmapheresis*;
Transplantation
- From:The Journal of the Korean Society for Transplantation
2014;28(1):39-42
- CountryRepublic of Korea
- Language:English
-
Abstract:
Immunologic responses of infants and younger children differ from those of adults. Therefore, application of different pretransplant strategies for antibody depletion in younger ABO-incompatible transplant recipients is appropriate. A 12-month-old male infant with end stage renal disease after acute tubular necrosis was scheduled to undergo kidney transplantation from an ABO-incompatible living donor. He did not undergo pretransplant plasmapheresis, as the titer of the anti-ABO antibody was less than 1:4. After kidney transplantation, posttransplant renal function and anti-ABO titers were stable until posttransplant 2 years.
