Delayed Recovery of Sedation by Continuous Midazolam Infusion in an ESRD Patient on Peritoneal Dialysis: A Case Report.
- Author:
Hye Jin CHOI
1
;
So Young KIM
;
Hae Jin CHOI
;
Hyun Sik PARK
;
Seon Ung YUN
;
Byeong Joo BAE
;
Jung Hwan PARK
;
Jong Ho LEE
;
Young Il JO
Author Information
1. Division of Nephrology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. nephjo.kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Midazolam;
Deep sedation;
Kidney failure;
chronic;
Peritoneal dialysis
- MeSH:
Aged;
Benzodiazepines;
Deep Sedation;
Heart Failure;
Humans;
Intensive Care Units;
Kidney Failure, Chronic;
Midazolam;
Peritoneal Dialysis;
Pneumonia;
Renal Dialysis;
Renal Insufficiency;
Respiration, Artificial
- From:Korean Journal of Nephrology
2010;29(6):834-838
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Midazolam, a benzodiazepine derivatives, is widely used in intensive care unit for sedation of patients who require mechanical ventilation. Although midazolam has a short acting time, it might cause a prolonged sedation, especially in patients with renal failure. We report the case of a 76-year-old man who received peritoneal dialysis and showed prolonged sedation after stopping continuous infusion of midazolam. The patient who has received maintenance hemodialysis for five months admitted in intensive care unit to manage pneumonia and severe congestive heart failure. In ICU, hemodialysis was transferred to peritoneal dialysis due to severe cardiac dysfunction. He was treated with mechanical ventilation under sedation with midazolam. However, even though stopping midazolam, deep sedation by midazolam was not restored. The patient completely recovered from sedation after 280 hours.
