A case of propofol-induced anaphylaxis.
- Author:
In Kwon CHUNG
1
;
Seong Woo JEON
;
Sung Uk KIM
;
Jong Won SOHN
;
Duk Won JUNG
;
Min Kyu JUNG
;
Sung Kook KIM
Author Information
1. Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. swjeon@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Propofol;
Anaphylaxis;
Conscious sedation
- MeSH:
Aged;
Anaphylaxis;
Conscious Sedation;
Edema;
Eggs;
Endoscopy;
Epinephrine;
Exanthema;
Eyelids;
Fabaceae;
Female;
Hemodynamics;
Humans;
Hypersensitivity;
Hypotension;
Lip;
Ovum;
Oximetry;
Oxygen;
Physical Examination;
Propofol;
Pruritus;
Respiratory Insufficiency;
Steroids;
Stress, Psychological;
Thorax
- From:Korean Journal of Medicine
2010;79(5):549-552
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Propofol is widely used for sedation during endoscopy. Hemodynamic compromise and respiratory depression might occur under propofol sedation, whereas anaphylaxis is rare. We recently experienced this rare side effect. A 71-year-old woman suffering from substernal chest discomfort underwent endoscopic examination under propofol sedation. She denied any history of allergic reaction to drugs or foods such as beans and eggs. After completion of the endoscopic examination, she developed a whole-body rash with pruritus and edema of her face, including the eyelids and lips. Hypotension was seen on physical examination, and her oxygen saturation was decreased on pulse oximetry. She recovered completely after treatment with epinephrine, an antihistamine, and steroids, with supportive care. Anaphylaxis to propofol is a rare side effect, and prompt treatment is mandatory when it develops.
