Clinical Trials of Tavegyl in Dermatologic Field.
- Author:
Choong Sang KIM
;
Jai Il YOUN
;
Yoo Shin LEE
;
Soon Bok LEE
;
Yang Ja PARK
;
Dong Kil BYUN
;
Won HOUH
- Publication Type:Original Article ; Clinical Trial
- MeSH:
Clemastine*;
Eczema;
Humans;
Skin;
Sleep Stages;
Urticaria
- From:Korean Journal of Dermatology
1974;12(2):33-37
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clinical trials were done to obtain ifnormation on the clinical efficacy, tolerance and side effects of a new antihistarnine, Mecloprodine(Tavegyl), in various skin disordetrs. A total of 48 patients suffered from various skin disorders as urticaria, eczema etc. v ere treated with 2mg. daily for 3 days to 15 days according to state of disorders. The results are as follows. 1. Improvement was noticed in 79.2% of total patients(38/48). 2. Tavegyl was efiective in all 8 cases of acute urticaria and most cases(7/8) of urticaria factitia. 3. Among 19 cases of chronic urticaria, improvement was noticed in 13 cases(68. 49). Improvement was alsa noticed in all 6 cases of eczema. 5. Drowsiness and weakness cccurred in 6.2% of cases(3/48).
