Metastatic Pulmonary Calcification in a Patient with Adult T-Cell Leukemia/Lymphoma.
10.3904/kjm.2014.87.6.750
- Author:
Soojung KIM
1
;
Won Chan KANG
;
Sun Woong KIM
;
Yoon Jeong LEE
;
Wookyoun KIM
;
Hyun Jeong KIM
;
Hong Ghi LEE
Author Information
1. Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. mlee@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Adult T cell leukemia/lymphoma;
Human T lymphotropic virus type 1;
Calcification, pathologic
- MeSH:
Adult*;
Bone Marrow;
Calcinosis;
Humans;
Hypercalcemia;
Leukemia-Lymphoma, Adult T-Cell;
Lung;
Lymphatic Diseases;
Parathyroid Hormone;
T-Lymphocytes*;
Technetium Tc 99m Medronate;
Thrombocytopenia
- From:Korean Journal of Medicine
2014;87(6):750-755
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that is geographically clustered, mirroring areas endemic for human T-cell lymphotropic virus type 1 infection. Most patients with ATLL present with aggressive manifestations such as severe hypercalcemia, lymphadenopathy, hepatosplenomegaly, and bone marrow involvement with progressive thrombocytopenia. We herein report a case of a patient with ATLL exhibiting increased uptake in both lungs as shown on a bone scan using 99mTc-methylene diphosphonate. This finding is thought to have been caused by metastatic calcification associated with ectopic parathyroid hormone production.
