Clinical Analysis for the Result after Curative Resection of Esophageal Cancer.
- Author:
Jae Ik LEE
1
;
Phil Jo CHOI
;
Mee Sook ROH
Author Information
1. Department of Thoracic and Cardiovascular Surgery, College of Medicine, Dong-A University, Busan, Korea. pjchoi@donga.ac.kr
- Publication Type:Original Article
- Keywords:
Esophageal neoplasms;
Lymph node excision;
Survival
- MeSH:
Carcinoma, Squamous Cell;
Esophageal Neoplasms*;
Esophagectomy;
Female;
Hospital Mortality;
Humans;
Lymph Node Excision;
Male;
Mortality;
Neoadjuvant Therapy;
Operative Time;
Prognosis;
Retrospective Studies;
Survival Rate
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2004;37(4):356-363
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Esophageal cancer is an aggressive disease with a poor prognosis. Recently, every effort has been made to improve the long term survival, but the general prognosis for patients with this disease remains poor. In this study, we reviewed 8 years of experiences with esophageal cancer patients managed in our department at Dong-A University Hospital and evaluated the effectiveness of cervical lymph node dissection performed selectively. MATERIAL AND METHOD: From January 1995 to August 2003, 70 patients underwent esophagectomy for esophageal cancer in our department. Among them, 51 patients who underwent curative resection, had no double primary tumors and no neoadjuvant therapy were analyzed retrospectively. In most patients, intrathoracic esophagectomy and cervical esophago-gastrostomy was performed. Since 1997, 3-field lymph node dissection was performed selectively. RESULT: There were 46 men and 15 women. The median age was 60 years. The tumor was located in the upper third part in 10 patients (19%), middle third in 21 (41%), and lower third in 20 (40%). Majority of the patients (90%) had squamous cell carcinoma. Cervical anastomosis was made in 41 patients, and intrathoracic anastomosis in 10. 2-field lymph node dissection was done in 40 patients, and 3-field lymph node dissection in 11. The pathologic staging were as follows: stage I in 9 patients (17.6%), IIA in 20 (39.2%), IIB in 7 (13.7%), III in 11 (21.6%), IVA in 2 (3.9%), and IVB in 2 (3.9%). The in-hospital mortality was 3.9% (2 patients) and complications occurred in 24 patients (47%). Overall actuarial 1, 3, and 5-year survival rates were 74.4%, 48.4%, and 48.4% including operative mortality. The 4-year survival rate did not differ significantly between 3-field lymph node dissection group (50.5%) and 2-field lymph node dissection group (48.9%). In 3-field lymph node dissection group, the respiratory complications were more frequent and operative time was significantly longer. CONCLUSION: We think that curative resection for esophageal cancer can be performed with acceptable mortality, and aggressive surgical approach may improve the long term survival. even for advanced stages. Effectiveness of 3-field lymph node dissection needs further investigations.
