Annual Report on External Quality Assessment in Diagnostic Genetics in Korea (2002).
- Author:
Hyoun Chan CHO
1
;
Sun Hee KIM
;
Sung Sup PARK
;
Sun Young KONG
;
Hee Jin KIM
;
Hye Shim CHOI
;
Jae Seok KIM
;
Eui Chong KIM
;
Suk Ja PARK
;
Jong Woo PARK
;
Soon Pal SEO
;
Kyung Soon SONG
;
Yu Kyung LEE
;
Se Ik JOO
;
Hyun Sook CHI
Author Information
1. Diagnostic Genetics Subcommittee, The Korea Association of Quality Assurance for Clinical Loboratory, Seoul, Korea.
- Publication Type:Review
- Keywords:
External quality assurance;
Diagnostic genetics;
Cytogenetics;
Molecular genetics
- MeSH:
Acidosis, Lactic;
Apolipoproteins E;
Cytogenetics;
Education;
Genetics*;
Korea*;
MELAS Syndrome;
Mitochondrial Encephalomyopathies;
Molecular Biology;
Mosaicism;
Muscular Atrophy, Spinal;
Quality Control;
Spinocerebellar Ataxias;
Stroke;
Tuberculosis
- From:Journal of Laboratory Medicine and Quality Assurance
2003;25(1):157-179
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The importance of quality control for dramatically growing genetic tests continues to be emphasized with increasing clinical demands. Diagnostic genetics subcommitee of KSQACP performed two trials for cytogenetic study in 2002. Cytogenetic surveys were performed by 33 laboratories and answered correctly in most laboratories except some problems in nomenclature and analysis for mosaicism and cytogenetics of neoplasia. The molecular genetic test surveys include M. tuberculosis, HCV, HBV, leukemia/lymphoma, ABO genotyping, ApoE genotyping, spinocerebellar ataxia (SCA), spinal muscular atrophy (SMA), and mitochondrial encephalomyopathy, lactic acidosis, and stroke like episodes (MELAS). HBV, SCA, SMA, MELAS tests were the first challenge of the genetic survey. Molecular genetic survey showed excellent results in most participants, however, ABO genotyping tests should be improved by new methods in a few laboratories. External quality assessment program for diagnostic genetics could be helpful to give participants many chances of continuous education and of interesting case materials.
