Balloon Cell Malignant Melanoma: A case report.
- Author:
Ji Young SEO
;
Soon Young KIM
;
Jeong Hee KANG
;
Young Ok KIM
;
Bang HUR
- Publication Type:Case Report
- Keywords:
Malignant melanoma;
Balloon cell
- MeSH:
Abdomen;
Humans;
Immunohistochemistry;
Incidence;
Lymph Nodes;
Melanoma*;
Middle Aged;
Neoplasm Metastasis;
S100 Proteins;
Skin;
Subcutaneous Tissue
- From:Korean Journal of Pathology
1999;33(7):537-539
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Balloon cell malignant melanoma (BCMM) is a rare histologic variant of malignant melanoma, which is composed either predominantly or entirely of large clear or foamy cells. The incidence of balloon cell malignant melanoma is about 0.15% of all cutaneous malignant melanomas. Recently, we experienced a case of cutaneous balloon cell malignant melanoma in the right lower abdomen with right inguinal and both axillary lymph node metastasis in a 56-year-old man. The cutaneous lesion was 4.5 3.5 cm in size, a well-demarcated black nodular mass, involving abdominal skin and subcutaneous tissue. The tumor was histologically composed of two types of tumor cells: predominant clear cell and focal, pigmented spindle cell. The nodal lesion was composed entirely of clear cells. Both clear and spindle cells showed positive reaction for S-100 protein and HMB-45 on immunohistochemistry.
