A Case of Rapidly Improved Menetrier's Disease after Short-term Treatment with Proton Pump Inhibitor.
- Author:
Hyun Jeong LIM
1
;
Seun Ja PARK
;
Jeong Ah SEO
;
Won MOON
;
Kyu Jong KIM
;
Moo In PARK
Author Information
1. Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea. parksj@ns.kosinmed.or.kr
- Publication Type:Case Report
- Keywords:
Menetrier's disease;
Proton pump inhibitor
- MeSH:
Breath Tests;
Cardia;
Dyspepsia;
Endosonography;
Female;
Gastritis, Hypertrophic;
Humans;
Immunoglobulin G;
Lymphoma;
Lymphoma, Non-Hodgkin;
Mucous Membrane;
Prognosis;
Proton Pumps;
Protons;
Stomach Neoplasms;
Urease;
Young Adult
- From:Korean Journal of Gastrointestinal Endoscopy
2008;36(2):83-86
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Menetrier's disease is a rare illness that is characterized by diffuse tremendous thickening of the gastric wall caused by excessive proliferation of the mucosa of unknown cause. An exact diagnosis is crucial due to the excellent prognosis as compared to other malignant lesions such as a gastric lymphoma and infiltrative gastric carcinoma. A 23-year-old woman presented with epigastric discomfort and dyspepsia. A rapid urease test, a test for H. pylori using serum IgG antibody, and a (13)C-urea breath test were all negative. A gastroscopic examination revealed a wide lesion encircling the lumen, which showed diffusely hard and thickened folds from an angle to the upper body near the cardia. Endoscopic ultrasonography showed diffusely hypoechoic thickness of the second wall layer, but the other wall layers were well preserved. The patient was diagnosed with Menetrier's disease without H. pylori infection, and the patient rapidly improved after short-term treatment with a proton pump inhibitor.
