Differences in Serum CEA Level between Colon and Rectal Cancer.
- Author:
Woon Seop SONG
;
Ho Jin JUN
;
Dong Kook PARK
;
Chan Young LEE
;
Jung Tak KIM
;
Doo Sun LEE
;
Min JUNG
;
Jong Kwon PARK
;
Jin Woo RHU
- Publication Type:Original Article
- Keywords:
Department of Surgery;
Dankook University College of Medicine
- MeSH:
Carcinoembryonic Antigen;
Colon*;
Colonic Neoplasms;
Humans;
Rectal Neoplasms*
- From:Journal of the Korean Society of Coloproctology
1998;14(3):393-398
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We investigated whether there is differences in serum level of carcinoembryonic antigen (CEA) between patients with colon and rectal cancer. Preoperative serum levels of CEA was determined in 65 patients with colon cancer and in 88 patients with rectal cancer. Cut-off value recommended by manufacturers is 5 ng/ml for CEA. At the recommended cut-off levels for CEA, overall sensitivity of CEA was 43.1 percent for colon and 42.0 percent for rectal cancer. In colon cancer CEA was elevated in 38.4, 46.2, 60 percent of patients with Dukes Stages B, C, and D, respectively. In rectal cancer CEA was elevated in 12.5, 31.6, 44.8, 84.6 percent of patients with Dukes Stages A, B, C, and D, respectively. In Stages B, and C, sensitivity of CEA was higher in colon than in rectal cancer, but the difference was not significant. In Stages D, sensitivity of CEA was higher in rectal cancer than in colon cancer, but the difference was not significant. In overall stages sensitivity of CEA was higher in colon than in rectal cancer, but the difference was not significant. The difference was not significant either in overall or in different stages of colon and rectal cancer.
