Analysis of 1,500 Kidney Transplantations at Sungkyunkwan University.
10.4285/jkstn.2014.28.1.25
- Author:
Jae Woong HONG
1
;
Milljae SHIN
;
Hyung Hwan MOON
;
Sanghoon LEE
;
Jong Man KIM
;
Jae Berm PARK
;
Choon Hyuck David KWON
;
Jae Won JOH
;
Suk Koo LEE
;
Sung Joo KIM
Author Information
1. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. kmhyj111@gmail.com
- Publication Type:Original Article
- Keywords:
Kidney transplantation;
Living donors;
Deceased donor;
Graft survival
- MeSH:
Allografts;
Follow-Up Studies;
Graft Survival;
Humans;
Incidence;
Kidney Failure, Chronic;
Kidney Transplantation*;
Kidney*;
Living Donors;
Male;
Retrospective Studies;
Tissue Donors;
Transplants;
Young Adult
- From:The Journal of the Korean Society for Transplantation
2014;28(1):25-35
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The most effective treatment for end-stage renal disease is kidney transplantation, and the number of kidney transplantations has shown a rapid increase. The aim of this study was to determine graft survival and functional outcome of 1,500 kidney transplant cases in a single center. We also investigated the factors affecting graft failure after kidney transplantation. METHODS: We retrospectively reviewed the clinical data of 1,500 pairs of donors and subsequent recipients who underwent kidney transplantation in Samsung Medical Center, from February 1995 to January 2012. RESULTS: The mean follow-up period was 2,241.5+/-1,609.4 days. There were 851 (56.7%) male recipients; 62 (4.1%) recipients were younger than 19 years old. Eleven (0.7%) cases were ABO blood group incompatible kidney transplant. A total of 531 (35%) deceased and 969 (65%) living donors were included. Among them, 191 (12.7%) recipients were experienced in graft failure. The most common cause of graft loss was chronic allograft nephropathy. One-year, 5-year, 10-year, and 15-year graft survival were 97.3%, 92.8%, 81.6%, and 75.1% (85.2% for living, 75.4% for deceased donor), respectively. Higher incidence of graft failure was observed in recipients who received deceased donor kidneys or experienced a rejection episode. CONCLUSIONS: In our experience, overall 10-year graft survival after kidney transplantation was 81.6%. This report demonstrated that the type of donor (living or deceased) and history of allograft rejection are the only significant factors affecting graft survival.
