Guanosine 5′-monophosphate-chelated calcium and iron feed additives maintains egg production and prevents Salmonella Gallinarum in experimentally infected layers.
10.4142/jvs.2017.18.3.291
- Author:
Hye Ji NOH
1
;
HeeKyong KIM
;
Su Jeong HEO
;
Hyang Hyun CHO
;
Hong Bum KOH
Author Information
1. Medinutrol Co., Ltd., Yeonggwang 57024, Korea.
- Publication Type:Original Article
- Keywords:
Salmonella Gallinarum;
feed additives;
layer;
organic mineral
- MeSH:
Body Weight;
Calcium*;
Cecum;
Eggs;
Guanosine*;
Iron*;
Liver;
Mortality;
Ovum*;
Poultry;
Poultry Products;
Salmonella Infections;
Salmonella*;
Spleen
- From:Journal of Veterinary Science
2017;18(3):291-97
- CountryRepublic of Korea
- Language:English
-
Abstract:
We evaluated the effects of guanosine 5′-monophosphate (GMP)-chelated calcium and iron (CaFe-GMP) on health and egg quality in layers experimentally infected with Salmonella Gallinarum. In this study, a CaFe-GMP feed additive was added to a commercial layer feed and fed to layers over a four-week period. All were inoculated with Salmonella Gallinarum. Body weight, mortality, clinical symptoms, and poultry production including feed intake, egg production, egg loss, and feed conversion rate were observed, and Salmonella Gallinarum was re-isolated from the liver, spleen, and cecum of the layers. All tested internal organs for the CaFe-GMP additive group exhibited significantly lower re-isolation numbers of Salmonella Gallinarum and less severe pathological changes than those in the control group, indicating that the CaFe-GMP feed supplement induced bacterial clearance and increased resistance to Salmonella Gallinarum. Additionally, due to the inhibitory action of CaFe-GMP on the growth of Salmonella Gallinarum, the CaFe-GMP additive group exhibited better egg production, including a higher laying rate and fewer broken eggs. The results suggest that a 0.16% CaFe-GMP additive may help prevent salmonellosis in the poultry industry.
