The Association between 24-hour Ambulatory Blood Pressure Monitoring Parameters and Plsam Atrial Natriuretic Peptide in CAPD Patients.
- Author:
Seok Joon SHIN
1
;
Byung Soo KIM
;
Young Ok KIM
;
Ho Cheol SONG
;
Seung Hun LEE
;
Yong Soo KIM
;
Eui Jin CHOI
;
Yoon Sik CHANG
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. drsong@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Continuous ambulatory peritoneal dialysis;
Atrial natriuretic peptide;
Ambulatory blood pressure monitoring
- MeSH:
Atrial Natriuretic Factor;
Blood Pressure;
Blood Pressure Monitoring, Ambulatory*;
Cardiovascular Diseases;
Humans;
Hypertension;
Linear Models;
Peritoneal Dialysis, Continuous Ambulatory*;
Plasma;
Renal Dialysis
- From:Korean Journal of Nephrology
2005;24(4):586-593
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The plasma concentration of atrial natriuretic peptide (ANP) has been shown to be a volume marker and be useful to predict cardiovascular disease in hemodialysis patients, so we investigate the association between 24-hour ambulatory blood pressure monitoring (ABPM) parameters and the plasma concentrations of ANP. METHODS: Plasma concentrations of ANP of 52 CAPD patients were measured and the patients were divided into the high ANP (>40 pg/mL) and the low ANP (<40 pg/mL) groups. We analyzed the association between the 24-hour ABPM parameters and the plasma concentrations of ANP of both groups. RESULTS: On a 24-hour ABPM record, a daytime mean systolic (167.1+/-22.4 vs. 142.2+/-23.5 mmHg, p<0.01) and diastolic (100.2+/-14.5 vs. 87.9+/-19.2 mmHg, p<0.05) blood pressure and a nighttime mean systolic (162.5+/-31.1 vs. 136.1+/-33.2 mmHg, p<0.01) and diastolic (94.3+/-16.8 vs. 84.3+/-14.9 mmHg, p<0.05) pressure were significantly increased in the high ANP group. In a simple linear regression analysis, daytime mean diastolic pressure was best correlated with the plasma concentrations of ANP (r=0.53, p<0.05). In peritoneal equilibrium test, a daytime mean systolic (168.7+/-18.1 vs. 128.4+/-11.8 mmHg, p=0.024) and diastolic (99.3+/-11.5 vs 80.3+/-8.3 mmHg, p=0.028) pressure were significantly increased in high transporter group. CONCLUSION: A 24-hour ABPM parameters are correlated with the concentrations of plasma ANP, so the plasma concentration of ANP may be useful for the assessment of the volume status and the treatment of hypertension in CAPD patients.
