The Effect of Aqueous Humor Suppressants on the Duration of Intravitreal Perfluorocarbon Gas Bubble in Rabbits.
- Author:
Gyu Won RYU
1
;
Young Il KIM
;
Il Han YUN
Author Information
1. Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
- Publication Type:Original Article
- Keywords:
Aqueous humor supprassants;
Intravitreal perfluorocarbon gas duration
- MeSH:
Absorption;
Aqueous Humor*;
Rabbits*;
Sulfur Hexafluoride
- From:Journal of the Korean Ophthalmological Society
2001;42(3):507-511
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Although the process by which intravitreal perfluorocarbon gas is absorbed is incompletely understood, it is known that considerable absorption of intravitreal perfluorocarbon gas occurs through the aqueous humor. The aim of the study was to evaluate experimentally the effect of topical aqueous humor suppressants on the intravitreal perfluorocarbon gas bubble duration. METHODS: After sulfur hexafluoride and perfluoropropane were injected intravitreally in ten rabbits, we measured the time of gas bubble disappearance in eyes treated with topical aqueous humor suppressants and in those not treated. RESULTS: The mean time(+/-SD) to disappearance of 0.4 cc of sulfur hexafluoride was 6.0+/-0.71 days, which was prolonged to 8.0+/-0.71 days with topical aqueous humor suppressants. The mean time(+/-SD) to disappearance of 0.2 cc perfluoropropane was 14.8+/-0.84 days, while it was prolonged to 22.0+/-1.58 days with topical aqueous humor suppressants. CONCLUSIONS: Sulfur hexafluoride and perfluoropropane intravitreal gas bubbles last longer in rabbit eyes treated with aqueous humor suppressants than in fellow control eyes.
