Generalized Multiple Fixed Drug Eruption.
- Author:
Young Keun KIM
;
Jung Bock LEE
- Publication Type:Original Article
- MeSH:
Antipyrine;
Barbiturates;
Criminals;
Drug Eruptions*;
Extremities;
Humans;
Male;
Neck;
Numismatics;
Phenobarbital;
Phenolphthalein;
Pigmentation;
Quinine;
Skin;
Young Adult
- From:Korean Journal of Dermatology
1978;16(5):409-413
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The term "fixed drug eruption" was coined by Louis Brocq in 1894 to describe a special type of reaction to antipyrine. It is now known that many drugs can cause a fixed drug eruption. Notorious offenders have included phenolphthalein, quinine and barbiturates. We present a case of multiple fixed drug eruption appearing in a 20 year-old male patient who has generalized slate-blue colored pigmentation on neck, trunk and extremities. The area of total pigmented skin lesions are over 50% of body surface. We could confirm the fixed drug eruption by positive phenobarbital provocation test.
