Visceral Fat Mass Has Stronger Associations with Diabetes and Prediabetes than Other Anthropometric Obesity Indicators among Korean Adults.
10.3349/ymj.2016.57.3.674
- Author:
Suk Hwa JUNG
1
;
Kyoung Hwa HA
;
Dae Jung KIM
Author Information
1. Ajou University School of Medicine, Suwon, Korea.
- Publication Type:Multicenter Study ; Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Diabetes mellitus;
obesity;
visceral fat
- MeSH:
Absorptiometry, Photon;
*Adiposity;
Adult;
Anthropometry;
Asian Continental Ancestry Group/*statistics & numerical data;
Biomarkers/blood;
Body Mass Index;
Cross-Sectional Studies;
Diabetes Mellitus/*ethnology;
Female;
Humans;
*Intra-Abdominal Fat;
Male;
Middle Aged;
Obesity/complications/*ethnology;
Odds Ratio;
Prediabetic State/*ethnology;
Prevalence;
Prospective Studies;
Republic of Korea/epidemiology;
Waist Circumference
- From:Yonsei Medical Journal
2016;57(3):674-680
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: This study determined which obesity measurement correlates the best with diabetes and prediabetes. MATERIALS AND METHODS: This cross-sectional study enrolled 1603 subjects (611 men, 992 women; age 30-64 years) at the Cardiovascular and Metabolic Diseases Etiology Research Center. Body mass index, waist circumference, waist-height ratio, waist-hip ratio, waist-thigh ratio, and visceral fat were used as measures of obesity. Visceral fat was acquired using dual-energy X-ray absorptiometry (DXA). The prevalences of diabetes and prediabetes were defined using the criteria in the American Diabetes Association 2015 guidelines. RESULTS: After adjusting for age and other potential confounding factors, participants with a visceral fat mass in the upper 10th percentile had a higher odds ratio (OR) for diabetes and prediabetes than the upper 10th percentile of other adiposity indices [men, OR=15.9, 95% confidence interval (CI)=6.4-39.2; women, OR=6.9, 95% CI=3.5-13.7]. Visceral fat mass also had the highest area under the curve with diabetes and prediabetes in both men (0.69, 95% CI=0.64-0.73) and women (0.70, 95% CI=0.67-0.74) compared to other anthropometric measurements of obesity. CONCLUSION: Visceral fat mass measured using DXA is an indicator of diabetes or prediabetes, due to its ability to differentiate between abdominal visceral and subcutaneous fat.
