Prostate Cancer Detection Rate of Rebiopsy in Patients with an Initial Diagnosis of Atypical Small Acinar Proliferation of the Prostate.
10.4111/kju.2009.50.3.237
- Author:
Jung Woo OH
1
;
Yun Beom KIM
;
Seung Ok YANG
;
Jeong Ki LEE
;
Yoon Jung KIM
;
Tae Young JUNG
;
Hong Bang SHIM
Author Information
1. Department of Urology, Seoul Veterans Hospital, Seoul, Korea. urodoct@hotmail.com
- Publication Type:Original Article
- Keywords:
Atypical small acinar proliferation;
Biopsy;
Prostatic neoplasms
- MeSH:
Biopsy;
Humans;
Male;
Prostate;
Prostate-Specific Antigen;
Prostatic Neoplasms
- From:Korean Journal of Urology
2009;50(3):237-240
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Atypical small acinar proliferation (ASAP) denotes the presence of suspicious glands with insufficient cytological architecture for a definitive prostate cancer diagnosis. We evaluated the subsequent prostate cancer detection rate of rebiopsy in patients with an initial diagnosis of ASAP. MATERIALS AND METHODS: Between January 2003 and December 2006, 1,416 men with suspected prostate cancer underwent a transrectal ultrasound-guided prostate biopsy, and 214 (15.1%) were diagnosed as having ASAP. Ninety-five of the 215 patients underwent at least one more biopsy. We evaluated the cancer detection rates after rebiopsy. RESULTS: In men with ASAP, 36 patients (37.9%) had prostate cancer. The cancer detection rates of the 1st, 2nd, and 3rd rebiopsies were 30.5%, 23.8%, and 40%, respectively. Mean patient age and prostate-specific antigen did not differ significantly between the prostate cancer and noncancer groups after rebiopsy. Prostate volume, however, was significantly smaller in the cancer group (p<0.05). CONCLUSIONS: Our results showed a detection rate for prostate cancer of 37.9% after an initial diagnosis of ASAP, which indicates that an initial diagnosis of ASAP mandates rebiopsy.
