Diffusion-weighted MR Imaging of Hypoxic-Ischemic Encephalopathy.
- Author:
Hye Young CHOI
1
;
Dae Seob CHOI
;
Jae Wook RYOO
;
Jae Min CHO
;
Eun Sook KO
;
Tae Beom SHIN
;
Jae Beom NA
;
Nak Cheon CHOI
Author Information
1. Department of Radiology, Gyeongsang National University Medical School, Korea. choids@gsnu.ac.kr
- Publication Type:Original Article
- Keywords:
Brain;
Hypoxia;
Magnetic resonance (MR);
Diffusion MR
- MeSH:
Anoxia;
Basal Ganglia;
Brain;
Cerebral Cortex;
Humans;
Hypoxia-Ischemia, Brain
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2008;12(1):49-54
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study was to determine the characteristics of hypoxic-ischemic encephalopathy (HIE) on diffusion-weighted imaging (DWI) and the role of DWI for the diagnosis of HIE. MATERIALS AND METHODS: Six patients with HIE underwent MRI including DWI. MR examinations were performed within 4 - 32 days (mean, 11.8 days) after hypoxic brain insult. We assessed the distribution of the lesions and compared the DWI and T2, FLAIR images for the subjective conspicuity of the lesions. RESULTS: In all patients, symmetrical hyperintense lesions were demonstrated in the bilateral basal ganglia on T2, FLAIR, and DWI. On ADC map image, the lesions were hypointense in four of six patients and isointense in other two patients. Lesion conspicuity on DWI was higher than on T2 and FLAIR images in four of six patients and similar in other two patients. For the involvement of the cortex and subcortical white matter, in five of six patients, bilateral symmetric hyperintense lesions were seen on T2, FLAIR, and DWI. Lesion conspicuity on DWI was higher than on T2 and FLAIR images in three of them and similar in other two patients. On ADC map image, the lesions showed hypointensity in three of five patients and isointensity in other two patients. For the involvement of the deep cerebral white matter, T2, FLAIR, and DWI showed bilateral symmetric hyperintense lesions in four of six patients. Among them, Lesion conspicuity on DWI was higher than on T2 and FLAIR images in only one patient. CONCLUSION: HIE is characterized by symmetrical hyperintense lesions in the bilateral basal ganglia, cerebral cortex, and white matter on DWI and the lesions are more conspicuously demonstrated on DWI than on T2 and FLAIR images.
