A Case of Melanosis Coli: A Case with history of rectal instillation of petroleum.
- Author:
Jae Jun KIM
;
Su Gang CHA
;
Hyun Chae JUNG
;
Yong Bum YOON
;
In Sung SONG
;
Kyoo Wan CHOI
;
Chung Yong KIM
- Publication Type:Original Article
- MeSH:
Administration, Rectal*;
Cathartics;
Colon;
Colonic Neoplasms;
Colonic Polyps;
Female;
Hemorrhoids;
Humans;
Lipofuscin;
Macrophages;
Melanosis*;
Middle Aged;
Mucous Membrane;
Petroleum*
- From:Korean Journal of Gastrointestinal Endoscopy
1991;11(1):109-112
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Melanosis coli is the brownish black discoloration of the colon due to accumulation of pigment containing macrophages in lamina propria. The nature and source of this pigment is controversial but many studies have suggested that the pigment is related to lipofuscin. Melanosis coli has been reported to be closely associated with prolonged administration of anthraquinone purgatives. But this condition is sometimes associated with colonic polyp colon cancer, rediation therapy or non-anthraquinone purgatives administration. Moreover the fact that melanosis coli could be found in subjects who never used purgatives suggested that, even though chronic consumption of anthraquinone purgatives seems to play a major role, other factors may be involved in the pathogenesis of melanosis coli. We presented a case of melanosis Coli in a 47-year-old female with history of rectal instillation of petroleum for control of hemorrhoids.
