A Strain of Nocardia cyriacigeorgica Isolated from a Patient with Pulmonary Infection.
10.5145/KJCM.2008.11.2.136
- Author:
Hye Ryong OH
1
;
Young Sook KIM
;
Sook Jin JANG
;
Xue Min LI
;
Won Yong KIM
;
Geon PARK
;
Dae Soo MOON
;
Young Jin PARK
Author Information
1. Department of Laboratory Medicine, Chosun University Medical School, Gwangju, Korea.
- Publication Type:Case Report
- Keywords:
Nocardia cyriacigeorgica;
Respiratory tract infections;
16S rRNA
- MeSH:
Agar;
Anemia, Aplastic;
Cough;
European Continental Ancestry Group;
Female;
Fever;
Genes, rRNA;
Hospitalization;
Humans;
Korea;
Lupus Erythematosus, Systemic;
Middle Aged;
Muramidase;
Nocardia;
Odors;
Respiratory Tract Infections;
Sequence Analysis;
Sprains and Strains;
Sputum;
Tuberculosis
- From:Korean Journal of Clinical Microbiology
2008;11(2):136-140
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nocardia cyriacigeorgica is an aerobic gram-positive rod that has mostly been reported as an opportunistic pathogen. Since molecular methodologies were introduced to identify species, infections caused by N. cyriacigeorgica have been reported. The patient was a 51-year-old woman with aplastic anemia, systemic lupus erythematosus, and disseminated tuberculosis, who was admitted to Chosun University Hospital with a history of fever and productive cough. During her hospitalization, sputum cultures were taken and a bacterium suspicious of acitinomycetes grew five times. It was a gram-positive rod that was also partially acid-fast on modified Kinyoun stain and resistant to lysozyme. After 24 h of incubation, cultures of the sputum onto sheep's blood agar plates (BAP) demonstrated rough, chalky, and white colonies with a characteristic earthy odor. Based on the above results, the presumptive identification of Nocardia species was made. To identify species of this isolate, 16S rRNA gene sequence analysis was taken and showed 99.9% homology to N. cyriacigeorgica DSM44484(T). The results of biochemical tests were compatible with other reports of N. cyriacigeorgica. As a result, this isolate was identified as N. cyriacigeorgica. Herein, we present a first report of N. cyriacigeorgica isolated from a patient with pulmonary infection in Korea.
