A Case of Severe Hypertension associated with Growth Hormone Therapy.
- Author:
Nyeon HEO
;
Chang Hee OH
;
June HUH
;
Phil Soo OH
;
Hong Jin LEE
;
Hae Sun YOON
- Publication Type:Case Report
- Keywords:
Growth hormone therapy;
Hypertension;
Blood pressure
- MeSH:
Adolescent;
Blood Pressure;
DNA, Recombinant;
Fetal Growth Retardation;
Growth Hormone*;
Human Growth Hormone;
Humans;
Hypertension*;
Male;
Nevus;
Noonan Syndrome;
Pseudotumor Cerebri;
Recurrence;
Renal Insufficiency, Chronic;
Slipped Capital Femoral Epiphyses;
Sodium
- From:Journal of Korean Society of Pediatric Endocrinology
2001;6(1):77-84
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The use of recombinant DNA technology to produce human growth hormone has resulted in a marked increase in availability of Growth Hormone(GH) to treat short stature due to GH deficiency and other conditions, such as Turner syndrome, familial short stature, chronic renal insufficiency and intrauterine growth retardation (IUGR). But, the GH therapy may result in the adverse events such as sodium and water retention, pseudotumor cerebri, slipped capital femoral epiphysis, growth of nevi, recurrence of tumor. We experienced a case of severe hypertension associated with GH therapy in a 14-year-old male who presented high blood pressure up to 190/100 mmHg and normalized at 2-3 weeks after discontinuation of GH. Therefore, we think that the blood pressure should be carefully monitored during GH therapy.
