Clinical Effect of Nicardipine(Perdipine(R)) on Cerebrovascular Diseases.
10.4070/kcj.1984.14.1.151
- Author:
Soo Jeon CHOI
;
Won Sang YOO
- Publication Type:Original Article
- MeSH:
Blood Pressure;
Calcium;
Deglutition;
Flushing;
Headache;
Humans;
Memory;
Nicardipine;
Paresthesia;
Tinnitus
- From:Korean Circulation Journal
1984;14(1):151-156
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Twenty-five patients with cerebrovascular diseases were administered Nicardipine, a calcium antagonist, in daily dose of 60 mg per orally for 8-12 weeks during the year of 1983, to evaluate the efficacy of the drugs clinically. The following results were obtained. 1) General improvement rating was 80%. 2) Marked improvement(88%) were noted in subjective symptoms, especially of tinnitus, paresthesia and headache. significant improvement were noted in psychiatric(74%) and neurologic(71%) symptoms e.g disturbance of sleep, emotion, memory, speech, swallowing and muscle power. 3) In 13 hypertensive patients, average blood pressure lowered from 163/96 to 138/83 mmHg in 4 weeks and maintained thereafter. 4) major adverse effect was facial flushing, noted in 4 patients(16%), which were transient and mild and allowed to contiume medication.
