Efficacy of Oral Fluconazole 300mg Once Weekly for Two Weeks in Treatment of Pityriasis Versicolor.
- Author:
Ok Hwan LIM
1
;
Jee Bum LEE
;
Seong Jin KIM
;
Young Ho WON
;
Seung Chul LEE
Author Information
1. Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea. schul@chonnam.ac.kr
- Publication Type:Original Article
- Keywords:
Fluconazole;
Pityriasis versicolor
- MeSH:
Dizziness;
Female;
Fluconazole*;
Humans;
Male;
Pityriasis*;
Tinea Versicolor*
- From:Korean Journal of Dermatology
2002;40(12):1493-1497
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was designed to assess the efficacy, tolerability and safety of oral fluconazole in the treatment of pityriasis versicolor(PV). METHODS: Fifty-nine patients, 48 males and 11 females aged 12-57(mean 30 years) were enrolled in this study. Oral fluconazole in 300mg single dosage once weekly for 2 weeks was administered. Clinical and mycological evaluation by global assessment, Wood's lamp examination, and KOH mount was performed. Evaluation was done before and after treatment, at week 1, 2, 3, 4 and 6. RESULTS: Forty-two patients(71.2%) showed clinical and mycological response at week 6. Tolerability of the drug was acceptable while two patients experienced mild dizziness during the therapy. Otherwise, there were no significant side effects to be attentioned. CONCLUSION: Oral fluconazole could be considered as an effective and safe alternative in the treatment of pityriasis versicolor.