Three Cases of Prevention Therapy to Reduce Perinatal HIV Transmission.
- Author:
Jae Yo LEE
1
;
Hyang Mi PARK
;
Se Hee HWANG
;
Kyeung Eun KIM
;
Hye Jung SHIN
;
Jae Yoon KIM
Author Information
1. Department of Pediatrics, National Medical Center, Seoul, Korea. nmcmpkjy@unitel.co.kr
- Publication Type:Case Report
- Keywords:
HIV;
Antiretroviral therapy
- MeSH:
Child;
Female;
Follow-Up Studies;
HIV;
Humans;
Infant;
Joints;
Mass Screening;
Mothers;
Pregnancy;
Pregnant Women;
United Nations;
Zidovudine
- From:Korean Journal of Pediatric Infectious Diseases
2011;18(1):85-90
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In 2008, the Joint United Nations Programme on HIV/AIDS (UNAIDS) estimated that about 430,000 children worldwide became infected with HIV, mostly through mother-to-child transmission (MTCT) during pregnancy, labor, delivery, or breast-feeding. The MTCT prevention program proved to be feasible and effective in reduction of perinatal HIV transmission. Three babies born from HIV-infected mothers were admitted to the National Medical Center in 2009. Only two women received antiretroviral (ARV) therapy during pregnancy, labor, and after delivery, and their infants received zidovudine (AZT) for 6 weeks. The outcome, after a follow-up period of 4 months to 16 months, was favorable in all patients. Thus, we emphasize the need for expansion of antenatal HIV screening of pregnant women, implemented for early HIV diagnosis and effective ARV therapy for reduction of perinatal HIV transmission.
