A Case of Adrenocortical Adenoma Causing Subclinical Cushing's Syndrome Mistaken for Liddle's Syndrome.
10.3803/jkes.2006.21.1.58
- Author:
Kyu Hong KIM
1
;
Kwang Hyun KIM
;
Ho Yoel RYU
;
Soo Min NAM
;
Mi Young LEE
;
Jang Hyun KOH
;
Jang Yel SHIN
;
Soon Hee JUNG
;
Choon Hee CHUNG
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
- Publication Type:Case Report
- Keywords:
Adrenocortical adenoma;
Liddle's syndrome;
Subclinical Cushing's syndrome
- MeSH:
Adrenocortical Adenoma*;
Adult;
Aldosterone;
Alkalosis;
Axis, Cervical Vertebra;
Cushing Syndrome*;
Fatigue;
Female;
Humans;
Hydrocortisone;
Hypokalemia;
Plasma;
Reference Values;
Renin
- From:Journal of Korean Society of Endocrinology
2006;21(1):58-62
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Subclinical Cushing's syndrome is defined as an autonomous cortisol hyperproduction without specific clinical signs of cortisol excess, but detectable biochemically as derangements of the hypothalamic-pituitary-adrenal axis function. We report a case of a 33-year-old woman with subclinical Cushing's syndrome caused by left adrenocortical adenoma, mistaken for Liddle's syndrome. The patient complained of fatigue. Laboratory findings showed metabolic alkalosis, hypokalemia, high TTKG (transtubular K concentration gradient), low plasma renin activity, and low serum aldosterone level, that findings implied as Liddle's syndrome. So we performed further study. Hormonal and radiologic studies revealed subclinical Cushing's syndrome with a left adrenal mass. The adrenal mass was resected and pathologically diagnosed as adrenocortical adenoma. After the resection of the left adrenal mass, patient's hormonal levels showed normal range.
