A Case of Lichenoid Drug Eruption Caused By Antituberculosis Drugs.
- Author:
Jee Ook KIM
1
;
Young Wook RYOO
;
Kyu Suk LEE
Author Information
1. Department of Dermatology, Keimyung University School of Medicine, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
Lichenoid drug eruption;
antituberculosis drugs
- MeSH:
Dermis;
Drug Eruptions*;
Ethambutol;
Extremities;
Histamine Antagonists;
Humans;
Hyperpigmentation;
Middle Aged;
Parakeratosis;
Rifampin;
Skin;
Weights and Measures
- From:Korean Journal of Dermatology
2000;38(12):1686-1687
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lichenoid drug eruption is lichenoid skin eruptions caused by certain drugs and compounds, and can be similar to lichenoid planus. A 59-year-old man who had taken antituberculosis drugs(Isoniazid, Rifampin, Ethambutol, Pyrazinamide) for 2months developed pruritic erythematous papules and plaques with silvery scales on the face, trunk and extremities. Histopathologic findings were hyperkeratosis, parakeratosis, hypergranulosis, band like lymphohistiocytic infiltration in the upper dermis and perivascular lymphohistiocytic infiltration in the deep dermis. He was treated with antihistamines and topical corticosteroid and then skin lesions slightly improved. 1 month after the termination of antituberculosis medication, skin lesions improved leaving hyperpigmentation.
