Gastric mucosal damage by bile acid.
10.12701/yujm.1992.9.2.342
- Author:
Hyun Hong CHO
;
Jeong Ill SUH
;
Keyong Hee LEE
;
Tae Nyeun KIM
;
Moon Kwan CHUNG
;
Hyun Woo LEE
;
Won Hee CHOI
;
Chang Heon YANG
- Publication Type:Original Article
- Keywords:
Stomach;
Bile acid;
Infalammation
- MeSH:
Animals;
Bile*;
Edema;
Gastric Mucosa;
Hydrogen-Ion Concentration;
Rats;
Rats, Sprague-Dawley;
Stomach;
Vasodilation
- From:Yeungnam University Journal of Medicine
1992;9(2):342-350
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To investigate the effect of bile acid on gastric mucosa, we performed biologic test using Sprague-Dawley rat. Mixture solution of TDCA 15mM and Hcl of pH 3 was given into stomach to one group and HCl of pH 3 was given into stomach to another group. The significant gastric mucosal change was vasodilation and edema, that was disappeared progressively. These findings suggest the bile acid and damage gastric mucosa.
