Intrafamilial transmission of HCV: comparison with HBV.
10.12701/yujm.1992.9.2.407
- Author:
Heon Ju LEE
- Publication Type:Original Article
- Keywords:
anti-HCV;
Epidemiology;
Intrafamilial transmission;
Sporadic infection;
HBsAg
- MeSH:
Blood Transfusion;
Diagnosis;
Epidemiology;
Hand;
Hepatitis B Surface Antigens;
Hepatitis C;
Humans;
Korea;
Liver Diseases;
Risk Factors;
Sensitivity and Specificity
- From:Yeungnam University Journal of Medicine
1992;9(2):407-415
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Among 85 patients with anti-HCV positive chronic liver disease, only 21.2% have past history of blood transfusion and over half the cases, they do not have any suspicious risk factors for HCV infection. 3 of 85 families show anti-HCV positive family members. On the other hand, 40 of 60 patients with HBsAg positive chronic liver disease show HBsAg positive family members. In Korea, HBV is transmitted mainly through vertical and intrafamilial infection but HCV disease might be rather horizontal and sporadic than vertical. To define the evident source of infection in sporadic hepatitis C, first of all, simple test with high sensitivity and specificity for diagnosis of HCV infection would be needed.
