Two Cases of Adult Onset Still's Disease with Concomitant Hemophagocytic Syndrome.
10.4078/jkra.2007.14.2.160
- Author:
Hyun Sook KIM
1
;
Keun Woo PARK
;
Soo Kyoung KIM
;
Ji Young KIM
;
Sung Hoon PARK
;
Jin Hyang SHIN
;
Sang Gyung KIM
;
Jung Yoon CHOE
Author Information
1. Department of Internal Medicine, The Catholic University of Daegu School of Medicine, Daegu, Korea. jychoe@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Adult onset Still's disease (AOSD);
Hemophagocytic syndrome
- MeSH:
Adult*;
Arthralgia;
Arthritis;
Disseminated Intravascular Coagulation;
Exanthema;
Fatal Outcome;
Female;
Fever;
Humans;
Korea;
Leukocytosis;
Liver Failure;
Lymphatic Diseases;
Lymphohistiocytosis, Hemophagocytic*;
Myocarditis;
Respiratory Distress Syndrome, Adult;
Still's Disease, Adult-Onset*
- From:The Journal of the Korean Rheumatism Association
2007;14(2):160-165
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Adult onset Still's disease is an rare inflammatory disease with the characteristic of fever, skin rash, arthralgia or arthritis, lymphadenopathy, leukocytosis and multiple systemic organ involvement. Its accurate pathogenesis has not been elucidated yet. Its clinical manifestation is also very diverse, from relatively mild symptoms to severe complications such as concomitant infection, liver failure, disseminated intravascular coagulation, myocarditis, adult respiratory distress syndrome, which may lead to death in some cases. Particularly, concomitant hemophagocytic syndrome is rare complication that could induce a fatal outcome. Thus it is important to diagnose early and start treatments. Until now, it has been reported in only one case of adult onset Still's disease in Korea. Here, we report two female cases of adult onset Still's disease with concomitant hemophagocytic syndrome.
