Two Cases of Klebsiella Pneumoniae Endogenous Endophthalmitis Treated with Sulperazone.
- Author:
Young Rok LEE
1
;
Yun Ho KIM
;
Kyoung Hoon HAHM
;
Min Cheol SHIN
Author Information
1. Department of Ophthalmology, College of Medicine, Hallym University, Chunchon, Korea. mcshin@hallym.ac.kr
- Publication Type:Case Report
- Keywords:
Endogenous endophthalmitis;
Klebsiella Pneumoniae;
Sulperazone
- MeSH:
Aged;
Amikacin;
beta-Lactamases;
Cefotaxime;
Ceftazidime;
Debridement;
Drug Resistance;
Endophthalmitis*;
Exophthalmos;
Female;
Humans;
Inflammation;
Klebsiella pneumoniae*;
Klebsiella*;
Male;
Middle Aged;
Orbital Cellulitis;
Vancomycin
- From:Journal of the Korean Ophthalmological Society
2005;46(3):554-559
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report and review 2 cases of Klebsiella Pneumoniae endogenous endophthalmitis showing multi drug resistance that were treated with sulperazone. METHODS: Sulperazone was administered to two patients with Klebsiella Pneumoniae endogenous endophthalmitis: a 51-year-old male with orbital cellulitis who showed no response to vancomycin, ceftazidime, and amikacin for 6days; and a 67-year-old female who showed no response to cefotaxime, and amikacin. RESULTS: Proptosis and inflammation began to improve after changing to sulperazone. Therefore, enucleation and debridement could be avoided. CONCLUSIONS: Good results were obtained by use of Sulperazone which inactivates beta-lactamase irreversibly and which showed bactericidal effect to multi drug resistant Klebsiella Pneumoniae endogenous endophthalmitis.
